siRNA drug targeting
Human Papilloma Virus (HPV) mediated cancers
EnhancedBio has established the unique RNAi’s drug development platform. It identifies the potent siRNAs that target and silence key genes in a sequence-specific manner, especially against undruggable targets for the treatment of cancer and other diseases.
EnhancedBio also has extensive experience in finding potent siRNAs with improved qualities such as low off-target effects, serum stability, immuno-stimulation and targeted delivery.
Human papillomavirus (HPVs) are circular, double-stranded DNA viruses, which are known for the development of cervical, oropharyngeal, anal, vulvovaginal, and penile cancers. HPV-associated carcinogenesis provides a classical model system for RNA interference (RNAi) based cancer therapies, because the viral oncogenes causes cancers expressed only in cancerous cells.